Prenatal Mancozeb Exposure, Excess Manganese, and Neurodevelopment at 1 Year of Age in the Infants’ Environmental Health (ISA) Study
نویسندگان
چکیده
منابع مشابه
Blood and Hair Manganese Concentrations in Pregnant Women from the Infants’ Environmental Health Study (ISA) in Costa Rica
Manganese (Mn), an essential nutrient, is a neurotoxicant at high concentrations. We measured Mn concentrations in repeated blood and hair samples collected from 449 pregnant women living near banana plantations with extensive aerial spraying of Mn-containing fungicide mancozeb in Costa Rica, and examined environmental and lifestyle factors associated with these biomarkers. Mean blood Mn and ge...
متن کاملCONGENITAL HEART DISEASE Neurodevelopment at 1 year of age in infants with congenital heart disease
Objective: To assess psychomotor development and neurological sequelae in infants after surgery for congenital heart defects. Design and setting: Single institution prospective cohort study. Patients: 90 of 112 consecutive surviving infants of less than 1 year of age, without brain anomalies, conditions, or syndromes associated with delayed mental development, who underwent cardiac surgery duri...
متن کاملAerial Application of Mancozeb and Urinary Ethylene Thiourea (ETU) Concentrations among Pregnant Women in Costa Rica: The Infants’ Environmental Health Study (ISA)
BACKGROUND Mancozeb and its main metabolite ethylene thiourea (ETU) may alter thyroid function; thyroid hormones are essential for fetal brain development. In Costa Rica, mancozeb is aerially sprayed at large-scale banana plantations on a weekly basis. OBJECTIVES Our goals were to evaluate urinary ETU concentrations in pregnant women living near large-scale banana plantations, compare their e...
متن کاملMaternal Blood Manganese and Early Neurodevelopment: The Mothers and Children’s Environmental Health (MOCEH) Study
BACKGROUND Manganese is an essential trace element and common component of water, soil, and air. Prenatal manganese exposure may affect fetal and infantile neurodevelopment, but reports on in utero manganese exposure and infant neurodevelopment are rare. OBJECTIVE This study was conducted to investigate a relationship between maternal blood manganese level and neurodevelopment of infants at 6...
متن کاملPrenatal Exposure to PBDEs and Neurodevelopment
BACKGROUND Polybrominated diphenyl ethers (PBDEs) are widely used flame retardant compounds that are persistent and bioaccumulative and therefore have become ubiquitous environment contaminants. Animal studies suggest that prenatal PBDE exposure may result in adverse neurodevelopmental effects. OBJECTIVE In a longitudinal cohort initiated after 11 September 2001, including 329 mothers who del...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2018
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp1955